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Graduate student creates educational guide about chemotherapy side effects for Colorado children’s hospital

Cancer-free for nearly 20 years, RIT graduate student Bryona Hamilton seeks to educate patients, survivors, and family members about potential chemotherapy side effects that can occur decades after treatment.

Hamilton will graduate this spring from RIT’s medical illustration MFA program after completion of her educational guide for the Children’s Hospital Colorado HOPE Cancer Survivorship Program in Aurora, Colo.

“There is a lot of change and a lot of unknowns that happen as a pediatric cancer patient graduates to a teen survivor and then an adult survivor, and that led me to want to make an educational pamphlet for the HOPE clinic about how chemotherapy can cause heart damage,” Hamilton said.

As a child, Hamilton was treated at Children’s Hospital Colorado for the blood cancer, Acute Lymphoblastic Leukemia, or ALL. Diagnosed before her second birthday, Hamilton underwent chemotherapy treatment until she was 5 years old.

<p>CREDIT</p>">

A colorful illustration of a human heart, showcasing various hues to represent different anatomical features.

Bryona Hamilton

This image shows Bryon Hamilton’s process work and the final heart illustration she created for the cover of an educational guide for cancer survivors.

Her thesis project educates people about a side effect that can weaken the heart years after cancer treatment. The therapy drugs, Anthracyclines, can damage heart muscle cells and prevent the left ventricle from efficiently pumping blood from the heart, Hamilton said. She and other survivors rely on periodic echocardiograms, or cardiac ultrasounds, to monitor their heart health.

During the COVID-19 epidemic, Hamilton saw the need for science communicators to translate complex medical information to the general public. With an undergraduate degree in cellular and molecular biology and a lifelong passion for art, Hamilton enrolled in RIT’s medical illustration MFA program, with an interest in pediatric cancer.

“I think the best part of the program is my peers,” she said. “I had always felt a little outside of science and outside of art because I had a foot in both doors. To be able to come to a collective space where I’m around individuals who share that experience, that's really valuable to me.”

Funds from an endowment established by Penny Kris-Etherton ’71 (food administration) for College of Health Sciences and Technology students will cover the debut printing costs for Hamilton’s pamphlet, called “Caring for Your Heart During Survivorship After Pediatric Cancer: A visual education guide on chemotherapy-induced cardiotoxicity.”

A QR code printed on the pamphlet will lead to a 3D model of a heart cell that Hamilton built as an extra layer of education, she said.

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A 3D model of a human heart featuring two tubes, illustrating anatomical structures and connections in a detailed manner.

Bryona Hamilton

This 3D modeled heart muscle cell shows where damage can occur from cancer therapy.

“People can scan the QR code and it takes them to an interactive model of a heart muscle cell (cardiomyocyte),” she said. “They can spin it around and click on it. It gives them that visual and an anatomical understanding of what is being impacted.”

Hamilton’s thesis advisory team includes her former pediatric oncologist, Dr. Brian Greffe, medical director of the Children’s Hospital Colorado HOPE Cancer Survivorship Program, who serves as her scientific content adviser.

“Dr. Greffe helps answer my questions about the research,” she said. “He has helped me tailor the graphics and narrow the language for a very specific audience. It has been great to talk with him now as an adult because he treated me as a child. It’s been rewarding.”

Hamilton hopes the materials she creates for the clinic will foster communication between patients and their care team.

“I think it’s important for patients to advocate for themselves,” Hamilton said. “Cancer can make you feel lost sometimes. Equipping patients with knowledge, I’m hoping, is kind of like giving them a lantern.”

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